Chronic Kidney Disease (CKD) is the gradual loss of kidney function, which prohibits kidneys from filtering waste and excess fluids from blood and excreting them through urine. When CKD reaches an advanced stage, it can allow dangerous levels of fluid, electrolytes, and urea to build up inside the body.
Causes of CKD include diabetes, high blood pressure, and other disorders.
In the early stages of CKD, there are few signs and symptoms of this disease and they typically do not become apparent until after the regression of kidney function.
Signs and symptoms of CKD include:
- Nausea and vomiting
- Loss of appetite
- Fatigue and weakness
- Sleep problems
- Changes in how much you urinate
- Decreased mental sharpness
- Muscle twitches and cramps
- Swelling of feet and ankles
- Persistent itching
- Chest pain, if fluid builds up around the lining of the heart
- Shortness of breath, if fluid builds up in the lungs
- High blood pressure or hypertension
Factors that may increase the risk of CKD include diabetes, high blood pressure, heart and blood vessel disease, smoking, obesity, race, family history of kidney disease, abnormal kidney structure, and older age.
Individuals with CKD may develop complications like fluid retention, high blood pressure, anemia, weak bones, poor nutritional health, and nerve damage. CKD may also increase the risk of heart and blood vessel disease.